烟台毓璜顶医院
鉴定专家
刘 娟
简 介
中共党员,国家司法鉴定人,办公室主任,硕士研究生学历,硕士学位,副主任技师,山东省干细胞工程技术研究中心办公室主任。
擅 长
法医遗传标记,法医STR分型,亲子鉴定,司法亲权鉴定,亲缘关系鉴定等。
教育背景
1. 2003/09-2006/06,昆明理工大学,生物化工,硕士
2. 1999/ 09-2003/06,昆明理工大学,材料与冶金工程,学士
承担项目情况
1.国家自然科学基金青年科学基金项目,81501313,Prx2基因在MEHP致精母细胞氧化损伤过程中的功能及其分子机制研究,2016.01-2018.12,21.6万,已结题,主持。
2.山东省重点研发计划,2017GSF18163,一种含TAT-PRDX2蛋白人精液冷冻保护剂的研制,2017.01-2018.12,12万,已结题,主持。
3. 中华医学会临床医学科研专项资金-生殖医学青年医师研究与发展项目,18010200749,抗氧化蛋白PRDX2对人精子冷冻损伤的保护作用及机制研究,13万,在研,主持。
学术论文
1. Juan Liu , Wenting Wang , Xin Liu ,et al. Supplementation of cryopreservation medium with TAT-Peroxiredoxin 2 fusion protein improves human sperm quality and function. Fertil Steril, 2018 ,110(6):1058-1066.
2. Juan Liu, Peng Zhu, Wen T. Wang, et al. TAT-peroxiredoxin 2 fusion protein supplementation improves sperm motility and DNA integrity in sperm samples from asthenozoospermic men. The Journal of Urology, 2016, 195(3): 706-12.
3. Juan Liu, Cheng T. Rong, Yan Li, et al. Vasectomy induces oxidative stress and up-regulates the expression of peroxiredoxins in mouse testis in short and early periods after surgery. The Journal of Urology, 2014, 191(6):1920-6.
4. Li N, Li S, Liu J, et al. Decreased expression of WNT2 in villi of unexplained recurrent spontaneous abortion patients may cause trophoblast cell dysfunction via downregulated Wnt/β-catenin signaling pathway. Cell Biol Int. 2017, 41(8): 898-907.
5. Xin Liu , Gensheng Liu , Juan Liu, et al. iTRAQ-based analysis of sperm proteome from normozoospermic men achieving the rescue-ICSI pregnancy after the IVF failure. Clin Proteomics. 2018 Aug 21;15:27.
6. X Liu , G Liu , J Liu , et al. Characterization of seminal plasma proteomic alterations associated with the IVF and rescue-ICSI pregnancy in assisted reproduction. Andrology. 2020 Mar;8(2): 407-420.
7. Hui Shi, Juan Liu, Peng Zhu, et al. Expression of peroxiredoxins in the human testis, epididymis and spermatozoa and their role in preventing H2O2-induced damage to spermatozoa. Folia Histochem Cytobiol. 2018;56(3):141-150.
专利著作
1.刘娟,朱鹏。一种含重组人PRDX4蛋白的人精液冷冻保护剂,中国,专利号:ZL 2015107590023。